The Litt laboratory translates NeuroEngineering research directly into patient care. We collaborate broadly across disciplines to invent, develop and test new technologies and apply them to basic and clinical research.
While epilepsy is the lab’s core focus, our multidisciplinary efforts span a variety of scientific and clinical areas, including brain-machine interfaces, functional neurosurgery, network and computational neuroscience, movement disorders, intra-operative and ICU monitoring, and a broad array of “brain network” disorders.
Brian's laboratory focuses on translating NeuroEngineering research directly into patient care through a collaboration between Neurology, Neurosurgery, Neuroscience, Psychology, and Engineering. While epilepsy is the lab's core focus, its multidisciplinary efforts span a variety of scientific and clinical interests including functional neurosurgery, network and computational neuroscience, movement disorders, intra-operative and ICU monitoring, and other brain network disorders. Specific areas of focus include automated implantable devices, understanding how seizures begin and spread, interpreting multi-scale neurosignals through machine learning, mapping functional networks and circuits in human brain, recording oscillations and modulating them via computer controlled electrical stimulation, and novel electronics technology for high fidelity electrophysiologic recording and brain modulation Dr. Litt is active as an active clinician, medical entrepreneur and inventor.
Dr. Davis’ research centers around utilizing both the advancing fields of invasive neurophysiology and neuroimaging to better localize epileptic networks in medication refractory epilepsy patients. She hopes that improving localization will enable epileptologists to better localize epileptic networks and assign individual patients to the most efficacious therapy, for example, seizure control devices, resective surgery, or continued medical management.
Dr. Wagenaar is interested in novel techniques to acquire, process and analyze neural data with an interest in development of brain computer interfaces and neural feedback devices to help treat and manage diseases and disabilities. Additionally, Dr. Wagenaar develops tools to help researchers do research, primarily in the area of using cloud computing to manage large datasets.
Dr Maus' research focuses on examining patient EEG recordings, especially recordings directly from the surface of the brain, in order to pinpoint exactly which part of the brain is malfunctioning and triggering seizures. We find that each patient has a different pattern of abnormal electrical activity at that start of seizures, and we are working to build devices with programs that are personalized to patients, which respond and treat their seizures.